Depth Estimation in Stereo Biomedical Images via Proxy-Supervised Deep Learning

In order to estimate depth through supervised deep learning-based stereo methods, it is necessary to have access to precise ground truth depth data. While the gathering of precise labels is commonly tackled by deploying depth sensors, this is not always a viable solution. For instance, in many applications in the biomedical domain, the choice of sensors capable of sensing depth at small distances with high precision on difficult surfaces (that present non-Lambertian properties) is very limited. It is therefore necessary to find alternative techniques to gather ground truth data without having to rely on external sensors. In this thesis, two different approaches have been tested to produce supervision data for biomedical images. The first aims to obtain input stereo image pairs and disparities through simulation in a virtual environment, while the second relies on a non-learned disparity estimation algorithm in order to produce noisy disparities, which are then filtered by means of hand-crafted confidence measures to create noisy labels for a subset of pixels. Among the two, the second approach, which is referred in literature as proxy-labeling, has shown the best results and has even outperformed the non-learned disparity estimation algorithm used for supervision.