Sintesi riduttiva di 3,3'-azossipiridine a partire da 3-nitropiridine

My thesis work focuses on the possibility of synthesizing azoxypyridines from the corresponding nitro derivatives through an experimentally very simple approach that involves the use of a base in combination with an alcohol as reducing agent. In the first part of this work, the reaction conditions were optimized using 3-nitropyridine as representative substrate. In the second part of this work, the thus optimised protocol was applied to a series of 3-nitropyridine substituted derivatives. Some of these substrates have actually led to the achievement of the corresponding desired azoxypyridine products. In future, it will be necessary to carry out further studies on the applicability of the optimized reaction conditions to other substituted nitropyridine substrates.