A novel marker for heart failure: Cross sectional area assessment in a large vein by conductance catheter.

Scivoletto, Salvatore (2015) A novel marker for heart failure: Cross sectional area assessment in a large vein by conductance catheter. [Laurea magistrale], Università di Bologna, Corso di Studio in Ingegneria biomedica [LM-DM270] - Cesena, Documento ad accesso riservato.
Documenti full-text disponibili:
[img] Documento PDF
Full-text non accessibile

Download (3MB) | Contatta l'autore


The present study investigates the feasibility of a new application able to check the heart failure status in a patient through the estimation of the venous distension. In this way it would be possible to follow up patients, avoiding invasive or expensive exams such as cardiac catheterization and echocardiography. Moreover, the devices would also be able to diagnose the decline of the disease, in order to allow a new adaptation to therapy, and vice versa to check the improvement in the patient’s conditions after the CRT device implant. This thesis is essentially divided into three parts: an analytical model was used to obtain an estimation of the error committed for the calculation of the CSA and to understand how the accuracy and sensitivity depend on the different configurations of the electrodes and the catheter position inside the vein; secondly, an in-vitro experiment was carried out in order to verify the practical feasibility for these kinds of measurements, in a very simplified model; in the end, several animal experiments were done to test the in-vivo practicability of the proposed method. The obtained results showed the feasibility of this approach. In fact, the error committed in the estimation of CSA, during the animal experiments, can be considered acceptable (CSAerror_max ≈ -14%). Moreover, it has been demonstrated that the conductance catheter allows assessing, not only the vein CSA, but also the breathing of the animal.

Tipologia del documento
Tesi di laurea (Laurea magistrale)
Autore della tesi
Scivoletto, Salvatore
Relatore della tesi
Correlatore della tesi
Corso di studio
Ordinamento Cds
Parole chiave
vein, distension, CSA, cross, sectional, area, heart, failure
Data di discussione della Tesi
19 Marzo 2015

Altri metadati

Gestione del documento: Visualizza il documento