WISDoM: Wishart Distributed Matrices Multiple Order classification. Definition and application to fMRI resting state data.

Mengucci, Carlo (2018) WISDoM: Wishart Distributed Matrices Multiple Order classification. Definition and application to fMRI resting state data. [Laurea magistrale], Università di Bologna, Corso di Studio in Fisica [LM-DM270]
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Abstract

In this work we introduce the Wishart Distributed Matrices Multiple Order Classification (WISDoM) method. The WISDoM Classification method consists of a pipeline for single feature analysis, supervised learning,cross validation and classification for any problems whose elements can be tied to a symmetric positive-definite matrix representation. The general idea is for informations about properties of a certain system contained in a symmetric positive-definite matrix representation (i.e covariance and correlation matrices) to be extracted by modelling an estimated distribution for the expected classes of a given problem. The application to fMRI data classification and clustering processing follows naturally: the WISDoM classification method has been tested on the ADNI2 (Alzheimer's Disease Neuroimaging Initiative) database. The goal was to achieve good classification performances between Alzheimer's Disease diagnosed patients (AD) and Normal Control (NC) subjects, while retaining informations on which features were the most informative decision-wise. In our work, the informations about topological properties contained in ADNI2 functional correlation matrices are extracted by modelling an estimated Wishart distribution for the expected diagnostical groups AD and NC, and allowed a complete separation between the two groups.

Abstract
Tipologia del documento
Tesi di laurea (Laurea magistrale)
Autore della tesi
Mengucci, Carlo
Relatore della tesi
Correlatore della tesi
Scuola
Corso di studio
Indirizzo
Curriculum E: Fisica applicata
Ordinamento Cds
DM270
Parole chiave
Machine Learning,Probability Models,fMRI,Alzheimer's Disease,Bio Physics,Data Analysis
Data di discussione della Tesi
23 Marzo 2018
URI

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